Vessel spatial analysis · Multiplex imaging · Open workflows

Computational Pathology Lab

Reproducible computational pathology for vascular biology, tumor microenvironment analysis, imaging mass cytometry, and translational cancer research.

VeSpAvessel spatial analysis
IMCmultiplex imaging workflows
6public software repositories
Openreproducible research tools

Research theme

Turning tissue images into measurable vascular and spatial biology

The Computational Pathology Lab builds analytical pipelines for extracting quantitative information from histological and multiplex tissue images. The group connects anatomical pathology, bioinformatics, image analysis, spatial biology, and computational modeling to study vascular remodeling, drug distribution, and tumor microenvironment organization.

VA

Vascular image analysis

Automated vessel segmentation, morphology extraction, and spatial distribution metrics from histological images.

DP

Digital pathology

Whole-slide and annotation workflows that translate expert pathology questions into repeatable quantitative analyses.

SB

Spatial biology

Cell neighborhoods, tissue architecture, vascular remodeling, and tumor microenvironment organization.

IMC

Imaging Mass Cytometry

Multiplex imaging workflows for channel preparation, segmentation, phenotyping, and spatial statistics.

DD

Drug distribution modeling

Computational links between vascular architecture, tissue context, and therapy delivery patterns.

AI

AI-assisted biomarkers

Careful machine learning for candidate biomarker discovery, validation, and biological interpretation.

WF

Reproducible pipelines

Documented Python, Nextflow, QuPath, and HPC workflows built for reuse and transparent analysis.

OS

Open science

Maintainable software, public repositories, and adaptable methods for interdisciplinary research.

Selected projects

Current work

Selected projects span vessel spatial analysis, multiplex imaging, computational pathology pipelines, and AI-assisted tumor microenvironment research.

VeSpA

Vessel Spatial Analysis for histological image analysis.

Team preview

People behind the work

A pathology-led, computation-enabled group connecting diagnostic expertise, bioinformatics, and reproducible software development.

Team profiles

Member cards load from editable JSON data.

Software

Open repositories

Open-source tools and workflows for VeSpA, imaging mass cytometry, QuPath-based annotation, Nextflow automation, and HPC execution.

Collaborate

Interested in spatial vessel analysis or computational pathology workflows?

Contact the lab to discuss collaborations, software, datasets, or translational research questions around tissue image analysis.